Brain and Cognition Research Study 09-2013
Brain Development and Learning Difficulties in Klinefelter Syndrome and Trisomy X/Triple X Syndrome

The MIND Institute at University of California, Davis is carrying out a study on the problems that some children have with thinking and reasoning about time, space, numbers and related areas of learning.
The study is funded by the National Institutes of Health, which is the main organization that gives money for research in the United States.
Dr. Tony Simon would like to invite your 7 to 14-year old child with Klinefelter syndrome or TrisomyX/Triple X syndrome to be part of the study.
Many children with Klinefelter syndrome or TrisomyX/Triple X syndrome score lower on language-based tasks compared to visuospatial skills.
We are studying the brain and how it produces this kind of thinking.
Once we know more, we plan to develop interventions to reduce learning problems in children with certain genetic conditions.

Children who take part in the study will play computer games, do paper and pencil tests, and have pictures taken of their brain using an MRI machine.
MRI scans do not involve any radiation.
All of the activities are safe and have been pre-Approved by our Institutional Review Board.
As part of this clinical research study, IQ achievement testing is carried out and parents will receive a letter describing the results in the mail a few weeks after completing the study.

Testing can be completed in two sessions of approximately 3 1/2 hours each day (or one full day).
After successful completion of this, your child will receive $60 in gift cards to thank them for their time and effort.
If needed, some funds may be available to assist families with travel accommodations to Sacramento, CA.
If you would like to find out more about taking part in this study and helping us learn about mind and brain development in children like your own, please contact one of the clinical research coordinators at The University of California, Davis MIND Institute at (916) 703-0408 or email us at

Medical Investigation of Neurodevelopmental Disorders
Clinical Research Information: (916) 703-0320
General Information: (916) 703-0280

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