Article Feb 2021; Results Dutch studie Adults with Triple-X Syndrome 2015-2018

18 May 2020
Evaluating the Scope of Language Impairments in a Patient with Triple X Syndrome: A Brief Report

Urbanus E, Swaab H, Tartaglia N,Cordeiro L, S van Rijn:
The behavioral profile of children aged 1–5 years with sexchromosome trisomy (47,XXX, 47,XXY, 47,XYY)

Article Nov 2018; German resource
Behavioral and psychological features in girls and women with triple-X syndrome.

"Children with sex chromosome trisomies:
parental disclosure of genetic status".

"Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia"

Developmental Medicine & Child Neurology
Accepted for publication 9th August 2013.
Published online

"A tale worth telling: the impact of the diagnosis experience on disclosure of genetic disorders"

Journal of Intellectual Disability Research
Volume 59 part 5 pp 474–486 may 2015

Dr. Sophie van Rijn of Leiden University (The Netherlands) wins the Gratama Science Award 2013 for her study of the extra x effects on social development.

The article as a result of her study:
"The Social Behavioral Phenotype in Boys and Girls with an Extra X Chromosome (Klinefelter Syndrome and Trisomy X):
A Comparison with Autism Spectrum Disorder"

Sophie van Rijn • Lex Stockmann • Martine Borghgraef • Hilgo Bruining • Conny van Ravenswaaij-Arts • Lutgarde Govaerts • Kerstin Hansson •
Hanna Swaab

Springer Science+Business Media New York 2013

Poor socio-economic status in 47,XXX - an unexpected effect of an extra X
Kirstine Stochholm, Svend Juul, Claus H. Gravholt
European Journal of Medical Genetics (20 March 2013)

"Attention-Deficit Hyperactivity Disorder Symptoms in Children and Adolescents with Sex Chromosome Aneuploidy: XXY, XXX, XYY, and XXYY"
Nicole R. Tartaglia, MD,* Natalie Ayari, BA,* Christa Hutaff-Lee, PhD,* and Richard Boada, PhD
J Dev Behav Pediatr. 2012 May 9.

The Dutch psychiatrist Maarten Otter wrote his second article regarding Triple X Syndrome.
Before you read the article it's important to read his introduction.

Article USA published!
A review of trisomy X (47,XXX)
Orphanet Journal of Rare Diseases 11 May 2010
Nicole R. Tartaglia, Susan Howell, Ashley Sutherland, Rebecca Wilson, Lennie Wilson.

Corresponding author:

''Autism, language and communication in children with sex chromosome trisomies'''
Published July 23, 2010

Written by:
Dorothy V M Bishop, Patricia A Jacobs, Katherine Lachlan, et al.

New Italian article published
May 5, 2010 Milaan

''Triple X syndrome: characteristics of 42 Italian girls and parental emotional response to prenatal diagnosis''

''Intestinal Atresia, Encephalocele, and Cardiac Malformations in Infants with 47,XXX:
Expansion of the Phenotypic Spectrum and a Review of the Literature''

Published February 16, 2010

Written by:
Soyhan Bağci, Andreas Müller, Axel Franz, Andreas Heydweiller,
Christoph Berg, Markus M. Nöthen, Peter Bartmann and Heiko Reutter.

"Neurocognitive outcomes of individuals with a sex chromosome
trisomy: XXX, XYY, or XXY: a systematic review"
Jan 5, 2010

July 2009
Article written by Drs Maarten Otter, psychiatrist in the Netherlands.

"Prenatal diagnosis and prognosis of triple X syndrome: 47, XXX"
Article written by Ben Hamouda H, et al, J Gynecol Obstet Biol Reprod (Paris) (2009), doi:10.1016/j.jgyn.2009.08.003
Service de pédiatrie,
Hôpital Universitaire Tahar Sfar
5111 Mahdia- Tunisie.

Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA. 2009.
Effects of sex chromosome aneuploidies on brain development: evidence from neuroimaging studies

Short description of the Triple X syndrome by the
”University of Michigan Medical Health System”.

Website of Genetics Home Reference; Your guide to understanding genetic Conditions"

Article about the origin of 47, XXY en 47, XXX aneuploidy;

“Margins of sexuality": the developmental differences associated with abnormal sexchromosomes are not always as devastating as once thought - includes related article”.

Article; "Gross and fine motor development in 45,X and 47,XXX girls"

Article; “No evidence of increased risk for schizophrenia or bipolar affective disorder in persons with aneuploidies of the sex chromosomes”.

Article; "Long term outcome in children of sex chromosome abnormalities "

Article; "Reduced size of the Amygdala in individuals with the 47,XXY en 47,XXX karyotypes”.

Article; "Neuropsychological and functional cognitive skills of 35 unselected adults with sex chromosome abnormalities"

Birth Defects Risk Factor Series by the
Texas Department of State Health Services with section on Triple X

Article; “Genetic Counseling for Sex Chromosome Abnormalities”

Article; "Intrauterine diagnosis of sex chromosome aneuploidy"

Article; "Sex Chromosome Abnormalities"

Article; "The growth of XXX females: population-based studies"

Canadian article 1983"The Triple X Chromosome Syndrome in Childhood: Recent Empirical Findings"

Article 2010 "Root length in the permanent teeth of women with an additional X chromosome (47,XXX females)".

Article 1987 "47,XXX females, sex chromosomes, and tooth crown structure"

UK Parents Not Given Enough Information About Fetal Genetic Disorders

[English section] [LINKS and ARTICLES]